TECHNICAL SUPPLEMENT · CHAPTER 26

The Pain-Dopamine Loop

If you have ever been told your pain is in your head, this is the chapter I wrote for you. Long pain turns the dopamine system down, and a turned-down dopamine system makes the pain louder — and both halves of that have been measured in living people. I will show you what the scans found, what the drugs did and did not do, the sleep disorder almost nobody screens for, and the one word in pain medicine that has done more harm than most drugs.

14 pages · 20 references, every one verified · written by Dr. Gurpreet Singh Padda, MD, MBA, MHP