TECHNICAL SUPPLEMENT · CHAPTER 17

The Trace Amines

Your brain runs a thermostat you have never heard of, and it decides how loudly your dopamine speaks. I spent years describing antipsychotics as D2 blockers before I understood that a second control layer was sitting in the same neuron, bolted to the same receptor. Here is what the trace amines do, why the cheese rule in psychiatry is real pharmacology, and what happened when somebody finally built a drug for it.

12 pages · 22 references, every one verified · written by Dr. Gurpreet Singh Padda, MD, MBA, MHP