DEEP DIVE · CHAPTER 8

The Inverted U

Dopamine and focus follow an inverted U curve. Focus improves as dopamine rises only up to a peak; past that point, thinking gets worse, the way it does under heavy pressure.

I prescribe stimulants, and I also tell families the part nobody says out loud: attention sits on a hill, not a ladder. Too little dopamine and you cannot focus. Too much and you cannot think, which is why the person who falls apart under pressure is not weak, they are saturated.

14 pages · 17 references, every one verified · written by Dr. Gurpreet Singh Padda, MD, MBA, MHP

Frequently asked questions

What is the dopamine inverted U?

The inverted U is the shape of the curve that links dopamine and focus. As dopamine rises, focus improves, but only up to a peak. Past that point, thinking gets worse, the way it does under heavy pressure. Attention sits on a hill, not a ladder: more helps only until you reach the top, and then more starts to hurt.

Can too much dopamine make it hard to focus?

Yes. Too little dopamine and you cannot focus. Too much and you cannot think. Past the top of the inverted U, extra dopamine makes thinking worse, not better. That is why the person who falls apart under pressure is not weak. They are saturated, pushed past the peak of the curve rather than short of effort or character.

What are signs of too much dopamine?

When it comes to focus, the sign is thinking that gets worse instead of sharper. On the inverted U, focus improves as dopamine rises until it peaks; past the peak, a person thinks less clearly, the way people do under heavy pressure. Chapter 8 covers what that means for stimulants, which the author prescribes, and what he tells families about them.